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Viz.ai Solutions For Cerebral Aneurysm And AAA Detection Evaluated In Real-World Studies
December 3, 2024—Viz.Ai announced new clinical data showing positive outcomes with real-world impact of the company's technology in clinical practice for treatment of patients with cerebral aneurysms or abdominal aortic aneurysms (AAAs).
The studies are being presented at RSNA 2024, the Radiologic Society of North America's annual scientific session held December 1-5 in Chicago, Illinois.
According to Viz.Ai, the first study, "Performance and Validation of a Machine Learning-Based Aneurysm Detection Tool in the Clinical Setting," assessed the performance of Viz Aneurysm through a retrospective evaluation of 703 head CTA exams from UC Irvine Health System in Orange, California.
The company reported that the Viz Aneurysm algorithm detected positive aneurysm cases with a sensitivity of 96.6% and specificity of 98.1%. The overall positive predictive value of Viz Aneurysm in this study was 82.4% and the negative predictive value was 99.7%.
Additionally, eight cases were detected with multiple aneurysms and 21 cases with aneurysms < 4 mm, suggesting Viz Aneurysm may be used to detect and manage patients with a lower risk of rupture, noted Viz.Ai.
"Our findings show that the Viz Aneurysm algorithm successfully detected most of the aneurysms in our clinical dataset and performed consistently across subset analyses," commented Jennifer E. Soun, MD, in the company's press release. "Viz Aneurysm's high accuracy shows its potential use to help detect and manage aneurysms in patients." Dr. Soun is an assistant professor, radiological services and neurology at University of California, Irvine School of Medicine in Irvine, California.
Viz.Ai stated that the second study, "Performance of AAA AI Triage Software on Real-World Patient Data," evaluated the performance of the Viz AAA algorithm across 341 CTA exams of the abdomen from Montefiore Health System in New York, New York.
In this retrospective analysis, the Viz AAA algorithm detected positive aneurysm cases with a sensitivity > 85%, whether cases with graft repair were included (86.5%) or not (88.6%), and specificity of 98.3%. Additionally, the investigators noted that 25 CTAs with AAA and graft repair were correctly identified as positive by the Viz AAA module, stated the company.
"These data suggest that this AI-triage tool is both highly sensitive and specific, indicating high reliability for cases determined as positive across our diverse patient scans," commented Matthew Lazarus, MD, in the Viz.Ai press release. "We believe incorporation of Viz AAA may help radiologists and other clinicians positively identify patients with AAA and potentially facilitate optimal treatment, management, and health outcomes." Dr. Lazarus is an assistant professor of radiology at Montefiore Medical Center and Albert Einstein College of Medicine in New York, New York.
December 3, 2024
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Depraved Predator Who Raped His Granddaughter And Gave Her Abortion When She Was 12 Dies In Prison
A TWISTED predator who raped his granddaughter and gave her an abortion when she was just 12 has died in prison.
Raymond Hodges preyed on the youngster from the age of five after offering to babysit while her mum was work.
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Raymond Hodges has died in prisonCredit: Media Wales
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Charlotte Wade, pictured aged 12, exposed abuser HodgesCredit: HotSpot MediaHe was jailed for 25 years in 2017 after being convicted of 24 offences against Charlotte Wade, who bravely waived her anonymity to speak out about the abuse.
It was today revealed Hodges, 78, died in February while serving his sentence at HMP Usk in Monmouthshire.
His cause of death was given as natural causes after he suffered a ruptured abdominal aortic aneurysm.
Hodges was Charlotte's stepdad's dad and would travel to her home in Wales once a month to stay with her.
The monster raped her for the first time when she was six after he moved from Essex to be closer to the family.
When Charlotte became pregnant aged just 12, Hodges' pinned her down and performed an excruciating abortion himself.
She bravely reported him to the police in 2016 after suffering years of horror abuse.
The following year, Hodges denied all but four charges against him - meaning Charlotte was forced to relive the ordeal at a trial.
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Gregg Wallace isn't the only BBC sexism scandal - but women are scared to talkHe was found guilty of the remaining 20 charges and later jailed for 25 years.
As he was sentenced, Judge Philip Harris-Jenkins said: "There was a long history of beatings, scaldings, and burns done in order to subject her to your control and there was further evidence of sexual pleasure you took from domineering this poor child."
Speaking in 2019, Charlotte told how she "fell to the floor" sobbing when she discovered her evil step-grandad had been convicted.
She added: "Speaking out has helped me move forward with my life – and I want to urge others to do the same.
"My sick grandad may have deprived me of a happy childhood, but I refuse to let him ruin my future.
"I'm slowing piecing my life back together. And it helps to know that he's rotting behind bars – and that my evidence helped to put him there."
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Charlotte Wade spoke out against the abuseCredit: HotSpot MediaHow to report a sexual assault
MU Researcher Finds Link Between Sleep Apnea And A Serious Heart Condition
Published November 29, 2024 at 2:11 PM CST
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A new study from University of Missouri researchers has found a link between breathing during sleep and a potentially fatal heart condition. The study, which was published in the Journal of Applied Physiology, focused on a potential link between obstructive sleep apnea and abdominal aortic aneurysms.
Obstructive sleep apnea is a condition in which a person repeatedly starts and stops breathing during sleep – causing difficulty breathing and other symptoms. A new study led by MU researchers used mice to show obstructive sleep apnea can increase the risk of abdominal aortic aneurysms, or triple A. When people repeatedly stop breathing during sleep, it causes something called intermittent hypoxia - which essentially means oxygen is only being taken in periodically. Researchers theorize this is the main factor that leads to Triple A development.
"These interruptions in breathing caused by OSA (Obstructive Sleep Apnea) are associated with significant health consequences, and the cardiovascular disease risk is one of the important risks caused by the OSA," said Dr. Neekun Sharma, the lead researcher on the study.
Triple A's are bulges that form in the major blood vessel that delivers blood from the heart. Sharma, who is also an assistant research professor with MU School of Medicine, said Triple A's are life-threatening and carry a high risk of rupture.
"Rupture can cause life threatening internal bleeding, like intra abdominal bleeding, and the symptoms of this rupture may include certain intense and persistent belly pain or the back pain," Sharma said. "You may have low blood pressure and a fast pulse."
Sharma said sleep apnea alone cannot cause Triple A's, but other risk factors can contribute to an increased risk. She said there are several actions that patients can take to lower their risk of developing triple A's.
"Following a heart healthy diet, staying physically active, quitting smoking. And the regular health checkup to, you know, look for the aortic diameter, an abdominal scan. You can go for a medical checkup every 6 months," Sharma said.
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