A guide to vaccinology: from basic principles to new developments
dengue internal bleeding :: Article Creator What Is Dengue Fever? Where did dengue originate? The origin of dengue is unclear, but scientists have recently proposed that dengue originated in Asian forests in an infectious cycle involving mosquitoes and primates. As early as 992, a dengue-like outbreak in humans was recorded in a Chinese medical encyclopedia. Epidemics of dengue-like illnesses were reported in the French West Indies in 1635 and in Panama in 1699. In 1771, Dr. Jose Sabater, a physician at the military hospital in San Juan, Puerto Rico, recommended treating dengue with small quantities of rum. At the time, the disease was called "break-bone fever." Where did this name come from? As you might guess, patients with the disease experienced a high fever accompanied by such severe bone and joint pains that they felt their bones were breaking. In 1780, Dr. Benjamin Rush recorded an epidemic of the disease later known as dengue i...